screw (something) up

Definition: to tighten and twist the muscles around your eyes, nose, or face.

(This phrasal verb has more than one meaning)

E.g.1: She screwed up her nose because there was a terrible smell in the room.
E.g.2: He screwed his face up and grunted as he tried to lift the heavy box.

This phrasal verb can be separated. (E.g. 2)